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Microsoft 365 vs Office 2021: Which One is Better?

Microsoft 365 VS Office 2021, in this article we will see together which one to buy. Both versions have specific advantages and disadvantages, and choosing correctly may not be very easy. That's why we decided to help you figure out which version of Office is right for you.

Microsoft 365 Vs Office 2021

Table of Contents

Microsoft 365 VS Office 2021: what is all about?

Microsoft 365 is a cloud-based solution that offers a comprehensive set of productivity applications and services. It includes well-known applications such as Word, Excel, PowerPoint and Outlook, as well as other powerful applications such as Teams, SharePoint, OneDrive and many others. As we have already written in our Microsoft 365 review, the main distinguishing feature of this Microsoft App is its subscription-based nature, which means that users pay a monthly or annual fee to access the services.

Office 2021, on the other hand, is a standalone application. It means that once purchased, you own a permanent license for the included applications such as Word, Excel and PowerPoint. By purchasing Office 2021, you do not receive the same cloud-based services included in Microsoft 365.

microsoft office 2021 vs 365

Key Differences Between Microsoft 365 and Office 2021 

The main differences between Microsoft 365 and Office 2021 concern the payment model, upgrades and new features, collaboration and connectivity, and access from anywhere. The choice between these two options will depend on the specific needs of the user or business, and it is important to examine these differences in detail to make an informed decision. Read on to find out the differences between the two versions. 

Payment Model

Microsoft 365 requires a regular payment in the form of a subscription, which can accumulate over time, Office 2021 provides a one-time payment for license purchase. This means that once you make the purchase, you will get the license permanently, without having to pay additional monthly fees. Although Microsoft 365 may offer more flexibility with ongoing upgrades, purchasing an Office 2021 product key on Mr. Key Shop saves you significant money and gives you complete control over your costs without monthly surprises. This option allows you to own a permanent license for essential applications such as Word, Excel and PowerPoint, with no monthly fees.

With Mr Key Shop, you can take advantage of special offers and competitive pricing, providing significant savings over subscription-based alternatives. After purchase, you will receive a link via email to quickly and smoothly download Office 2021. In addition, you will have complete control over your data and documents, keeping them local for privacy and security reasons. This way, you can use the powerful features of Office 2021 efficiently and without worrying about subscription deadlines or additional costs. It’s a smart investment for those looking for a durable and affordable solution for their productivity needs.

Read our guides on Office 2021 Professional Plus and how to install Office 2021 Home and Student.

office 2021 professional plus lifetime license key

Updates and New Features

When it comes to updates and new features, Microsoft 365 and Office 2021 present different approaches. The features of Microsoft 365 are constantly being updated and aim to constantly improve the user experience. This constant evolution ensures that you are always on the cutting edge of the latest technologies and that your work is supported by the latest innovations in productivity. If you are a single user, you should read our guide to Microsoft 365 Personal

On the other hand, Office 2021 takes a different approach. Updates are less frequent and new features are introduced only with later versions. This means that you may not have immediate access to the latest innovations. However, if you are satisfied with existing features and prefer some stability in your work environment, Office 2021 may be the right choice for you. Keep in mind that if you want to constantly benefit from the latest features, you may need to consider Microsoft 365.

Collaboration and Connectivity

In the context of collaboration and connectivity, Microsoft 365 and Office 2021 have significant differences.

Microsoft 365 stands out for its outstanding collaboration capabilities through cloud-based services. This productivity suite allows users to work synchronously on documents, share information in real time through tools such as Teams, and store their files securely on OneDrive. This cloud-based synergy is ideal for teams and companies looking to work together in an efficient and coordinated way, regardless of the physical location of the members.

On the other hand, Office 2021 does not offer the same level of cloud-based collaboration. Sharing and collaborating on documents can be more complex and require more manual effort. If your business does not require extensive collaboration or if you prefer to manage your documents locally, Office 2021 may be a suitable option. 

microsoft office 365 product key

Access from Anywhere

Speaking of access from anywhere, another significant difference between Microsoft 365 and Office 2021 emerges. Microsoft 365 is distinguished by its cloud-based nature, which allows users to access their applications and documents from any Internet-connected device. This flexibility is especially valuable for those who work remotely or on the move, as it allows them to maintain a seamless workflow from anywhere in the world. Whether you are in the office, at home or on the road, you are guaranteed to have all your productivity tools at your fingertips.

In contrast, Office 2021 requires applications to be installed on a specific device. This can result in some limitation in remote access, making it difficult to work off site or share documents on the go. If you need maximum mobility and access from anywhere, Microsoft 365 may be the best choice to meet your work needs. If remote work is not a priority for you, Office 2021 may still be a solid option, especially if you focus on working on a fixed device.

Benefits of Office 2021 and Microsoft 365

Microsoft 365 offers a number of key benefits that go beyond users’ expectations in terms of productivity and collaboration. First, users enjoy constant access to the latest features, thanks to continuous updates that keep the interface fresh and cutting-edge. This means that those using Microsoft 365 are always one step ahead in the world of technology and can take full advantage of the latest innovations.

In addition, the ability to collaborate in real time on documents and projects is a key aspect of Microsoft 365. Simultaneous sharing and editing of documents simplifies the work of teams and companies, improving efficiency and overall productivity. This feature is especially valuable for realities where collaboration is crucial.

Another major benefit of Microsoft 365 is access from anywhere. Because of the cloud-based nature, users can work from any Internet-connected device, making remote work more effective and eliminating restrictions related to geographic location. This is especially important in a world increasingly geared toward flexible work.

On the other hand, Office 2021 has different but equally valuable advantages. The absence of monthly fees is a clear attraction. Once a license is purchased, there are no additional recurring charges, which can be a significant advantage for those who prefer stable financial planning. Finally, some companies prefer Office 2021 because of its ability to keep data and documents local, thus preserving greater control and privacy. This is essential for those in sensitive industries where data protection is a priority. 

office 365 product key

Microsoft 365 and Office 2021: Available Versions and Apps 

Microsoft 365 and Office 2021 offer a range of versions and applications to meet different user needs. Let’s see what options are available.

Microsoft 365

Microsoft 365 has solutions available for every need. From proven plans for one person to plans for large companies. 

Microsoft 365 FamilyIdeal for families, it offers licenses for up to six users and includes applications such as Word, Excel, PowerPoint, Outlook and more.
Microsoft 365 PersonalDesigned for single users and includes the same applications as Microsoft 365 Family, but with a single license.
Microsoft 365 BusinessAimed at small and medium-sized businesses, it offers essential business applications, collaboration tools such as Teams, and business email services.
Microsoft 365 EnterpriseAimed at large enterprises, it offers a wide range of applications and services, advanced security and compliance options, and employee and device management tools.
Microsoft 365 Business BasicFor small businesses, it offers business email services and essential video conferencing tools.
Microsoft 365 Business StandardIt includes all the features of Microsoft 365 Business Basic and adds desktop applications such as Word, Excel and PowerPoint, as well as many other productivity tools.
Microsoft 365 Business PremiumIt offers everything included in Microsoft 365 Business Standard and adds advanced security and compliance features, as well as management tools for enterprise devices.
Microsoft 365 Apps for BusinessProvides access to essential productivity applications for businesses of all sizes.
Microsoft 365 Apps for EnterpriseDesigned for large enterprises, it offers advanced desktop applications along with advanced security features.

Office 2021

Office 2021 is available in several editions, including Office Home & Student 2021, Office Home & Business 2021, and Office Professional 2021. Each edition offers a selection of applications, including Word, Excel and PowerPoint. Office Home & Student 2021 is perfect for students and home users, while Office Home & Business 2021 is suitable for professionals working from home. Office Professional 2021 is designed for advanced business needs and includes tools such as Outlook and Access.

Choosing among the available versions and applications depends on your personal or business needs. It is important to consider what tools you need to maximize productivity and choose the version that best fits your particular case.

Here is a table with the available PC and Mac versions of Office 2021, the apps included for each version, and list prices:

VersionDeviceIncluded AppsList PriceDiscounted Price
Office Home & Student 2021PC Word, Excel, PowerPoint, OneNote€149.99Buy for €89.99
Office Home & Student 2021MacWord, Excel, PowerPoint, OneNote€149.99Buy for €99.99
Office Home & Business 2021MacWord, Excel, PowerPoint, Outlook, OneNote€299.99Buy for €99.99
Office Home & Business 2021PcWord, Excel, PowerPoint, Outlook, OneNote€299.99Buy for €109.99
Office Professional 2021PcWord, Excel, PowerPoint, Outlook, OneNote, Access, Publisher€579.99Buy for €109.99

Office 2021 AND Microsoft 365: Which one to choose?

The choice between Microsoft 365 and Office 2021 depends on individual and business needs. If you want constant access to the latest features, the ability to collaborate efficiently and work from anywhere, Microsoft 365 might be the best choice. On the other hand, if you prefer a single payment model and have specific privacy needs, you might opt for Office 2021. Both options offer excellent tools, but it is important to consider the key differences and assess your specific needs before making a decision.

office 2021 key


In conclusion, choosing between Microsoft 365 and Office 2021 is a significant decision that should be carefully weighed against your specific needs. Both options offer distinct advantages that can greatly affect your productivity and work experience.

Ultimately, the decision will depend on your priorities and the needs of your job or business. Carefully consider which aspects are most relevant to you: constant access to the latest features, advanced collaboration and mobility, or a more traditional solution with a single payment model. Regardless of your choice, both Microsoft 365 and Office 2021 offer excellent productivity tools that can greatly enhance your work.

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